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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CBX3 All Species: 41.82
Human Site: S145 Identified Species: 83.64
UniProt: Q13185 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13185 NP_009207.2 183 20811 S145 F L M K W K D S D E A D L V L
Chimpanzee Pan troglodytes XP_001161192 173 19690 S135 F L M K W K D S D E A D L V L
Rhesus Macaque Macaca mulatta XP_001086720 183 20781 S145 F L M K W K D S D E A D L V L
Dog Lupus familis XP_539136 204 23204 S166 F L M K W K D S D E A D L V L
Cat Felis silvestris
Mouse Mus musculus P23198 183 20837 S145 F L M K W K D S D E A D L V L
Rat Rattus norvegicus XP_001068590 183 20849 S145 F L M K W K D S D E A D L V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508853 184 20945 S146 F L M K W K D S D E A D L V L
Chicken Gallus gallus NP_989974 174 19759 S136 F L M K W K D S D E A D L V L
Frog Xenopus laevis NP_001083952 174 19890 S136 F L M K W K D S D E A D L V P
Zebra Danio Brachydanio rerio NP_001038867 174 19953 S136 F L M K W K D S D E A D L V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P05205 206 23167 V171 F L I Q F K G V D Q A E M V P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q946J8 445 48626 Y259 L I D N E K E Y D P T L N E L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.5 99.4 89.7 N.A. 99.4 93.4 N.A. 96.1 91.2 86.8 74.8 N.A. 42.2 N.A. N.A. N.A.
Protein Similarity: 100 94.5 99.4 89.7 N.A. 99.4 95.6 N.A. 97.8 92.9 91.8 83.6 N.A. 61.1 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 93.3 93.3 N.A. 40 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 93.3 93.3 N.A. 80 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 29.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 92 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 84 0 100 0 0 84 0 0 0 % D
% Glu: 0 0 0 0 9 0 9 0 0 84 0 9 0 9 0 % E
% Phe: 92 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 84 0 100 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 92 0 0 0 0 0 0 0 0 0 9 84 0 75 % L
% Met: 0 0 84 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 25 % P
% Gln: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 84 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 9 0 0 0 0 0 92 0 % V
% Trp: 0 0 0 0 84 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _